🧬 WHAT IS IGF-1?
You’ve probably seen IGF-1 mentioned anytime growth hormone comes up.
GH signaling stimulates production of insulin-like growth factor 1 (IGF-1), particularly in the liver, although other tissues can produce it too.
IGF-1 participates in growth, bone, muscle, and broader tissue biology. It also helps provide feedback within the GH signaling system.
Another useful distinction: GH itself is highly pulsatile, while IGF-1 is comparatively more stable.
One signal leads into another. 🧬